An incidence density sampling program for nested case-control analyses

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An incidence density sampling program for nested case-control analyses.

BACKGROUND The nested case-control design can be a very efficient approach to an epidemiological investigation. In order to obtain unbiased estimates of relative risk, controls should be selected by incidence density sampling, which involves matching each case to a sample of those who are at risk at the time of case occurrence. METHODS This paper presents a simple computer program for inciden...

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Sampling strategies in nested case-control studies.

A stratified version of nested case-control sampling which we call "countermatching" is presented. This design uses data available for all cohort members to obtain a sample for collecting additional information in a case-control substudy. Hitherto the only stratified sampling design for such studies has involved matching of controls to cases with respect to confounding variables. However, in so...

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15 صفحه اول

Analysis of Clinical Cohort Data Using Nested Case-control and Case-cohort Sampling Designs

K. Ohneberg1,2; M. Wolkewitz1,2; J. Beyersmann3; M. Palomar-Martinez4,5; P. Olaechea-Astigarraga6; F. Alvarez-Lerma7; M. Schumacher1 1Institute for Medical Biometry and Statistics, Medical Center University of Freiburg, Freiburg, Germany; 2Freiburg Center for Data Analysis and Modelling, University of Freiburg, Freiburg, Germany; 3Institute of Statistics, Ulm University, Ulm, Germany; 4Hospital...

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ژورنال

عنوان ژورنال: Occupational and Environmental Medicine

سال: 2004

ISSN: 1351-0711

DOI: 10.1136/oem.2004.014472